Scientific papers

1. Tan HT, Chek MF, Miyahara Y, Kim SY, Tsuge T, Hakoshima T, Sudesh K. Characterization of an (R)-specific enoyl-CoA hydratase from Streptomyces sp. strain CFMR 7: A metabolic tool for enhancing the production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate). J Biosci Bioeng. 2022 Aug 8:S1389-1723(22)00193-1. doi: 10.1016/j.jbiosc.2022.07.005. Epub ahead of print. PMID: 35953354.
2. Chek MF, Kim SY, Mori T, Kojima H, Hakoshima T. 
   Crystal structure of N-terminal degron-truncated human glutamine synthetase. 
   Acta Crystallogr F Struct Biol Commun. 2021 Nov 1;77(Pt 11):427-434. doi: 10.1107/S2053230X21010748. Epub 2021 Oct 29. PMID: 34726182.
3. Lim H, Chuah JA, Chek MF, Tan HT, Hakoshima T, Sudesh K.
   Identification of regions affecting enzyme activity, substrate binding, dimer stabilization and polyhydroxyalkanoate (PHA) granule morphology in the PHA synthase of Aquitalea sp. USM4. 
   Int J Biol Macromol. 2021 Jul 8;186:414-423. doi: 10.1016/j.ijbiomac.2021.07.041. Epub ahead of print. PMID: 34246679.
4. Kim SY, Mori T, Chek MF, Furuya S, Matsumoto K, Yajima T, Ogura T, Hakoshima T. 
   Structural insights into vesicle amine transport-1 (VAT-1) as a member of the NADPH-dependent quinone oxidoreductase family. 
   Sci Rep. 2021 Jan 22;11(1):2120. doi: 10.1038/s41598-021-81409-y. PMID: 33483563; PMCID: PMC7822847.
5. Tan HT, Chek MF, Lakshmanan M, Foong CP, Hakoshima T, Sudesh K.
   Evaluation of BP-M-CPF4 Polyhydroxyalkanoate (PHA) Synthase on the Production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) From Plant Oil Using Cupriavidus Necator Transformants.
   Int J Biol Macromol 2020 May 14;159:250-257. doi: 10.1016/j.ijbiomac.2020.05.064. Online ahead of print.
6. Chek MF, Kim SY, Mori T, Tan HT, Sudesh K, Hakoshima T.
   Asymmetric open-closed dimer mechanism of polyhydroxyalkanoate (PHA) synthase PhaC.
   iScience 2020 May 22;23(5):101084.doi: 10.1016/j.isci.2020.101084. Epub 2020 Apr 21.
7. Chek MF, Kim SY, Mori T, Arsad H, Samian MR, Sudesh K, Hakoshima T.
   Structure of polyhydroxyalkanoate (PHA) synthase PhaC from Chromobacterium sp. USM2, producing biodegradable plastics.
   Sci Rep. 2017 Jul 13;7(1):5312. doi: 10.1038/s41598-017-05509-4.

Books/Chapters/Reviews

1. Neoh SZ, Chek MF, Tan HT, Linares-Pastén JA, Nandakumar A, Hakoshima T, Sudesh K.
   Polyhydroxyalkanoate synthase (PhaC): The key enzyme for biopolyester synthesis.
   Current Research in Biotechnology. 2022 4:87-101. doi.org/10.1016/j.crbiot.2022.01.002.
2. Chek MF, Hiroe A, Hakoshima T, Sudesh K, Taguchi S.
   PHA synthase (PhaC): interpreting the functions of bioplastic-producing enzyme from a structural perspective.
   Appl Microbiol Biotechnol. 2019 Feb;103(3):1131-1141. doi:10.1007/s00253-018-9538-8. Epub 2018 Dec 3. Review.
3. Hiroe, A., Chek, M.F., Hakoshima, T., Sudesh, K., Taguchi, S. (2019). Synthesis of Polyesters III: Acyltransferase as Catalyst. In: Kobayashi, S., Uyama, H., Kadokawa, Ji. (eds) Enzymatic Polymerization towards Green Polymer Chemistry. Green Chemistry and Sustainable Technology. Springer, Singapore. https://doi.org/10.1007/978-981-13-3813-7_7